Menarini Group Obtains Exclusive Rights to Commercialize NEXPOVIO for the Treatment of Hematologic and Solid Tumor Oncology Indications in Europe (including the United Kingdom), Latin America and Other Key Countries Karyopharm to Receive $75 Million Upfront, then Eligible to Receive Up to $202.5 Million in Future Milestones, Plus Tiered, Double-digit Royalties on Net Sales

Florence (Italy) November 4th, 2021 – The Menarini Group announced today that the U.S. Food and Drug Administration (FDA) granted orphan drug designation (ODD) to SEL24/MEN1703 for the treatment of Acute Myeloid Leukemia (AML). SEL24/MEN1703 is a first-in-class, orally available, dual PIM/FLT3 inhibitor, in-licensed by Menarini from Ryvu Therapeutics, and currently investigated in the DIAMOND-01 trial as a single agent for the treatment of patients with relapsed/refractory AML.

Florence, Italy and Boston, Mass., October 20, 2021 – the Menarini Group (“Menarini”) and Radius Health, Inc. (“Radius”) (NASDAQ: RDUS) (collectively, the “Companies”) today announced positive topline results from the EMERALD study. The study was designed to evaluate elacestrant as a monotherapy versus the standard of care (SoC) for the treatment of ER+/HER2- advanced or metastatic breast cancer (mBC). There were two primary endpoints: progression-free survival (PFS) in the overall population and PFS in patients with tumors harboring Estrogen Receptor 1 (ESR1) mutations.

Singapore, 23 August, 2021 - A. Menarini Asia-Pacific Holdings Pte. Ltd., part of the leading Italian global biopharmaceutical company Menarini Group, signed a multi-year exclusive licensing agreement to assume the registration, sales, marketing, and distribution of the orally administered gabapentinoid, mirogabalin (brand name; TARLIGE®), in the Philippines, Malaysia and Singapore.

新加坡2021年7月22日 /美通社/ -- 作为全球规模最大的意大利生物制药公司之一，美纳里尼集团（Menarini Group）旗下美纳里尼亚太公司（A. Menarini Asia-Pacific Holdings Pte Ltd）今天宣布在中国完成对礼来公司（Eli Lilly and Company）Cialis®（希爱力®）品牌的收购。通过此次收购，美纳里尼将接管该品牌的所有权，并负责其所有销售、市场推广和分销工作。

Florence, Italy, 9th April 2021. “Who are the people depicted in the Primavera and why are they dancing in an orchard instead of a ballroom? “or “ Why was the Medusa painted on a shield?” These are just some of the questions posed by the young protagonists of the Pills of Art Junior series, now online in Italian and English on the Menarini Group YouTube channel, aimed at getting the younger generations interested in some of the world’s timeless masterpieces. These short videoclips reveal anecdotes, details and unprecedented curiosities on some of the most famous works of art, mainly from the Italian Renaissance period, thanks to simple and straightforward questions put by children and teenagers to the (almost) equally young art experts.